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 Vol 9: Screening for Autism Spectrum Disorders with the Brief Infant-Toddler Social and Emotional Assessment.


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This article is from PLoS ONE, volume 9.AbstractObjective: Using parent-completed questionnaires in preventive child health care can facilitate the early detection of psychosocial problems and psychopathology, including autism spectrum disorders ASD. A promising questionnaire for this purpose is the Brief Infant-Toddler Social and Emotional Assessment BITSEA. The screening accuracy with regard to ASD of the BITSEA Problem and Competence scales and a newly calculated Autism score were evaluated. Method: Data, that was collected between April 2010 and April 2011, from a community sample of 2-year-olds N = 3127, was combined with a sample of preschool children diagnosed with ASD N = 159. For the total population and for subgroups by childs gender, area under the Receiver Operating Characteristic ROC curve was examined, and across a range of BITSEA Problem, Competence and Autism scores, sensitivity, specificity, positive and negative likelihood ratios, diagnostic odds ratio and Youdens index were reported. Results: The area under the ROC curve 95% confidence interval, 95%CI of the Problem scale was 0.900.87–0.92, of the Competence scale 0.930.91–0.95, and of the Autism score 0.950.93–0.97. For the total population, the screening accuracy of the Autism score was significantly better, compared to the Problem scale. The screening accuracy of the Competence scale was significantly better for girls AUC = 0.97; 95%CI = 0.95–0.98 than for boys AUC = 0.91; 95%CI = 0.88–0.94. Conclusion: The results indicate that the BITSEA scales and newly calculated Autism score have good discriminative power to differentiate children with and without ASD. Therefore, the BITSEA may be helpful in the early detection of ASD, which could have beneficial effects on the childs development.



Autor: Kruizinga, Ingrid; Visser, Janne C.; van Batenburg-Eddes, Tamara; Carter, Alice S.; Jansen, Wilma; Raat, Hein

Fuente: https://archive.org/







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