Vol 10: Reduction in cardiovascular risk using a proactive multifactorial intervention is consistent among patients residing in Pacific Asian and non-Pacific Asian regions: a CRUCIAL trial subanalysis.Reportar como inadecuado



 Vol 10: Reduction in cardiovascular risk using a proactive multifactorial intervention is consistent among patients residing in Pacific Asian and non-Pacific Asian regions: a CRUCIAL trial subanalysis.


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This article is from Vascular Health and Risk Management, volume 10.AbstractBackground: Few trials have compared different approaches to cardiovascular disease prevention among Pacific Asian PA populations. The Cluster Randomized Usual Care versus Caduet Investigation Assessing Long-term-risk CRUCIAL trial demonstrated that a proactive multifactorial intervention PMI approach based on single-pill amlodipine-atorvastatin resulted in a greater reduction in calculated Framingham 10-year coronary heart disease CHD risk compared with usual care UC among hypertensive patients with additional risk factors. One-third of CRUCIAL patients resided in the PA region. The aim of this subanalysis was to compare two approaches to cardiovascular risk factor management PMI versus UC among patients residing in PA and non-PA regions. Methods: This subanalysis of the CRUCIAL trial compared treatment-related changes in calculated CHD risk among patients residing in PA and non-PA regions. Sensitivity analyses were conducted among men and women and those with and without diabetes. Results: Overall, 448 patients 31.6% resided in the PA region and 969 patients 68.4% resided in non-PA regions. The PMI approach was more effective in reducing calculated CHD risk versus UC in both PA −37.1% versus −3.5%; P



Autor: Cho, Eun Joo; Kim, Jae Hyung; Sutradhar, Santosh; Yunis, Carla; Westergaard, Mogens

Fuente: https://archive.org/







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