Vol 66: Predictors of New-Onset Widespread Pain in Older Adults: Results From a Population-Based Prospective Cohort Study in the UK.Report as inadecuate



 Vol 66: Predictors of New-Onset Widespread Pain in Older Adults: Results From a Population-Based Prospective Cohort Study in the UK.


Vol 66: Predictors of New-Onset Widespread Pain in Older Adults: Results From a Population-Based Prospective Cohort Study in the UK. - Download this document for free, or read online. Document in PDF available to download.

Download or read this book online for free in PDF: Vol 66: Predictors of New-Onset Widespread Pain in Older Adults: Results From a Population-Based Prospective Cohort Study in the UK.
This article is from Arthritis & Rheumatology Hoboken, N.j., volume 66.AbstractObjective: In older adults, widespread pain WP is common, although its etiology is unclear. This study sought to identify factors associated with an increased risk of developing WP in adults age ≥50 years. Methods: A population‐based prospective study was conducted. A baseline questionnaire was administered to subjects to collect data on pain, psychological status, lifestyle and health behaviors, and sociodemographic and clinical factors. Participants free of WP as defined by the American College of Rheumatology 1990 criteria for fibromyalgia were followed up for 3 years, and those with new‐onset WP at followup were identified. Logistic regression analyses were used to test the relationship between baseline factors and new‐onset WP. Multiple imputation was used to test the results for sensitivity to missing data. Results: In this population‐based study, 4,326 subjects 1,562 reporting no pain at baseline and 2,764 reporting some pain at baseline participated at followup. Of these participants, 800 18.5% reported a status of new WP at followup of whom, 121 7.7% had reported no pain at baseline and 679 24.6% had reported some pain at baseline. The majority of the study factors were associated with new‐onset WP. However, only a few factors showed a persistent association with new‐onset WP in the multivariate analysis, including age odds ratio OR 0.97, 95% confidence interval 95% CI 0.96–0.99, baseline pain status OR 1.1, 95% CI 1.08–1.2, anxiety OR 1.5, 95% CI 1.01–2.1, physical health‐related quality of life OR 1.3, 95% CI 1.1–1.5, cognitive complaint OR 1.3, 95% CI 1.04–1.6, and nonrestorative sleep OR 1.9, 95% CI 1.2–2.8. These associations persisted after adjustment for the presence of diffuse osteoarthritis OA, which led to a modest increase in model fit C‐statistic 0.738, compared with 0.731 in the model excluding diffuse OA. The results were not sensitive to missing data. Conclusion: Of the factors measured in this study, nonrestorative sleep was the strongest independent predictor of new‐onset WP.



Author: McBeth, John; Lacey, Rosie J.; Wilkie, Ross

Source: https://archive.org/







Related documents