Vol 12: Prognostic significance of XB130 expression in surgically resected pancreatic ductal adenocarcinoma.Report as inadecuate



 Vol 12: Prognostic significance of XB130 expression in surgically resected pancreatic ductal adenocarcinoma.


Vol 12: Prognostic significance of XB130 expression in surgically resected pancreatic ductal adenocarcinoma. - Download this document for free, or read online. Document in PDF available to download.

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This article is from World Journal of Surgical Oncology, volume 12.AbstractBackground: XB130 is a newly discovered adaptor protein for intracellular signal transduction; it is involved in gene regulation, cell proliferation, cell survival, cell migration, and tumorigenesis. However, its expression and role in pancreatic ductal adenocarcinoma PDAC have not been investigated. The present study was designed to clarify the prognostic significance of XB130 expression in PDAC. Methods: A total of 76 consecutive patients with surgically resected PDAC were retrospectively reviewed. XB130 expression was detected by immunohistochemical analysis on the paraffin-embedded tumour sections. Correlation between the expression of XB130 and clinicopathological parameters was analyzed. Results: XB130 expression was significantly upregulated in PDAC56.5%, 43-76 compared to normal pancreas 0%, 0-15; P 



Author: Zhang, Jianli; Jiang, Xiuli; Zhang, Jian

Source: https://archive.org/







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