Vol 7: Prognostic Significance of Metastatic Lymph Node Ratio in Patients with Gastric Cancer: an Evaluation in North-East of Iran.Report as inadecuate



 Vol 7: Prognostic Significance of Metastatic Lymph Node Ratio in Patients with Gastric Cancer: an Evaluation in North-East of Iran.


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This article is from Iranian Journal of Cancer Prevention, volume 7.AbstractBackground: In this study we have evaluated the prognostic impact of Metastatic Lymph node Ratio MLR in gastric cancer patients whose have undergone curative surgical resection. Methods: A total of 121 patients with gastric adenocarcinoma undergoing curative surgical resection R0 in our institutions between 2003 and 2010 have been included in this study. MLR has classified into 3 groups as follows: MLR0; 0, MLR1; 0-0.33 and MLR2; 0.34-1. We have used Kaplan-Meier method to calculate survival rates and log rank test to compare survival curves between groups. Cox proportional hazards model has utilized for multivariate analysis. Results: The median age of patients was 65 range; 32 to 89 with a male to female ratio of 91-30 3.03. 88 patients have undergone total gastrectomy 72.5% and 33 subtotal gastrectomy 27.5%. With a median total retrieved lymph node of 11 range; 6 to 44, the MLR0 to MLR2 has calculated in 2823.1%, 3125.6% and 62 51.2% patients respectively. MLR2 0.33 has significantly associated with higher Tumor stage T1-T2: 18.7% vs. T3: 56.2%, p=0.002. With a median follow up time of 12 months range; 2-88, the 3-year survival in patients with MLR0, MLR1 and MLR2 was 75.1%, 54.8% and 9.5% respectively p value



Author: Taghizadeh-Kermani, Ali; Yahouiyan, Seyede Zeinab; AliAkbarian, Mohsen; Seilanian Toussi, Mehdi

Source: https://archive.org/







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