Vol 9: Prognostic Significance of the Neutrophil-to-Lymphocyte Ratio in Primary Liver Cancer: A Meta-Analysis.Reportar como inadecuado



 Vol 9: Prognostic Significance of the Neutrophil-to-Lymphocyte Ratio in Primary Liver Cancer: A Meta-Analysis.


Vol 9: Prognostic Significance of the Neutrophil-to-Lymphocyte Ratio in Primary Liver Cancer: A Meta-Analysis. - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Descargar gratis o leer online en formato PDF el libro: Vol 9: Prognostic Significance of the Neutrophil-to-Lymphocyte Ratio in Primary Liver Cancer: A Meta-Analysis.
This article is from PLoS ONE, volume 9.AbstractThe neutrophil-to-lymphocyte ratio NLR is a useful biomarker that reflects systemic inflammation responses. However, the prognostic value of the NLR in patients with primary liver cancer PLC remains controversial. We performed a meta-analysis of 26 studies comprising 4,461 patients to evaluate the association between the pre-treatment NLR and clinical outcomes of overall survival OS and disease-free survival DFS in patients with PLC. The correlation between NLR and tumor characteristics or other inflammation-related parameters was also assessed. Data were synthesized using the random-effects model of DerSimonian and Laird, and the hazard ratio HR or odds ratio OR with 95% confidence interval CI was used to estimate effect size. Our analysis indicated that a high NLR predicted poor OS HR, 2.102; 95% CI: 1.741–2.538 and DFS HR, 2.474; 95% CI: 1.855–3.300 for PLC. A high NLR was associated with the presence of tumor vascular invasion OR: 1.889, 95% CI: 1.487–2.400; p



Autor: Xue, Tong-Chun; Zhang, Lan; Xie, Xiao-Yin; Ge, Ning-Ling; Li, Li-Xin; Zhang, Bo-Heng; Ye, Sheng-Long; Ren, Zheng-Gang

Fuente: https://archive.org/







Documentos relacionados