Vol 28: Pallidal deep brain stimulation for the treatment of DYT6 dystonia: a case report and review of literature.Reportar como inadecuado



 Vol 28: Pallidal deep brain stimulation for the treatment of DYT6 dystonia: a case report and review of literature.


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This article is from Medical Journal of the Islamic Republic of Iran, volume 28.AbstractLittle is known about the results of pallidal deep brain stimulation DBS in DYT6 dystonia. This will be the first report of DYT6 dystonia treated with pallidal DBS from Iran. A 21 years old male patient with DYT6 dystonia underwent bilateral deep brain stimulation. The target of DBS was the sensorimotor region of the posteroventral globus pallidus internus GPi. DBS parameters included an amplitude of 2.7 V, frequency of 160 Hz, and pulse width of 90 μs which were adjusted according to the patients response 12 months after surgery. Treatment outcome was measured by the patient’s Burke-Fahn-Marsden Dystonia Rating Scale BFMDRS score. Before surgery, the patients BFMDRS score was 32. However, BFMDRS score reduced to 7 at one year follow up after surgery 78% improvement of total score. Dystonic symptoms of extremities and mouth completely resolved. Also speech and swallowing function significantly improved. Although previous observations reported a poor to moderate response in speech, we found DBS as an effective treatment not only for dystonic features, but also for speech improvement of DYT6 dystonia.



Autor: Miri, Shahnaz; Shahidi, Gholam Ali; Parvaresh, Mansour; Rohani, Mohammad

Fuente: https://archive.org/







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