Vol 10: Onset of polyarticular juvenile idiopathic arthritis with both anti-cyclic citrullinated peptide antibodies and rheumatoid factor in a 3-year-old girl.Reportar como inadecuado



 Vol 10: Onset of polyarticular juvenile idiopathic arthritis with both anti-cyclic citrullinated peptide antibodies and rheumatoid factor in a 3-year-old girl.


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This article is from Pediatric Rheumatology Online Journal, volume 10.AbstractThis report describes 3 year old girl with the unusual presentation of polyarticular juvenile idiopathic arthritis JIA with anti-cyclic citrullinated peptide anti-CCP antibodies and a positive rheumatoid factor RF. She was initially treated with a nonsteroidal anti-inflammatory drug NSAID; ibuprofen followed by methotrexate MTX, 10 mg-m2-week and prednisolone 0.25 mg-kg-day, but these treatments were ineffective. Administration of tocilizumab, a humanized antihuman interleukin-6 receptor monoclonal antibody, promptly improved her clinical manifestations, and she has been in complete remission DAS28



Autor: Yasui, Kozo; Sakata, Sonoko; Ochi, Hideaki; Itamura, Shinji; Hirai, Kenta; Takenaka, Mieko; Mitani, Osamu; Ogawa, Kazunori; Iyoda, Kuniaki

Fuente: https://archive.org/







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