Vol 13: Leukocytes and systemic inflammatory response syndrome as prognostic factors in pulmonary embolism patients.Report as inadecuate



 Vol 13: Leukocytes and systemic inflammatory response syndrome as prognostic factors in pulmonary embolism patients.


Vol 13: Leukocytes and systemic inflammatory response syndrome as prognostic factors in pulmonary embolism patients. - Download this document for free, or read online. Document in PDF available to download.

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This article is from BMC Pulmonary Medicine, volume 13.AbstractBackground: Hemodynamic status and cardiac function are important factors for predicting pulmonary embolism PE prognosis. Although inflammation is considered a risk factor for deep vein thrombosis, the prognostic significance of both systemic inflammatory response syndrome SIRS and leukocytosis has not been elucidated. This study evaluates PE prognostic factors, including SIRS and leukocytes. Methods: This retrospective cohort study included 667 PE patients. Risk evaluation included SIRS and leukocytosis. A prediction model was developed based on independent predictors of 30-day mortality. Results: Fifty-seven patients 8.5% died within 30 days of PE. Multivariate analysis showed that SIRS satisfying the WBC criteria odds ratio OR, 2.8; 95% confidence interval CI, 1.5–5.4, altered mental status OR, 4.0; 95% CI, 1.8–8.7, shock OR, 2.6; 95% CI, 1.0-7.1, and right-to-left ventricle diameter ratio OR, 1.7; 95% CI, 1.0-2.8 were associated with 30-day mortality. SIRS criteria, including body temperature OR, 4.6; 95% CI, 1.4–14.8, heart rate OR, 2.0; 95% CI, 1.1–3.6, respiratory rate OR, 2.5; 95% CI, 1.4–4.6, and white blood cells WBC count OR, 1.9; 95% CI, 1.2–3.5 predicted short-term mortality following PE. The area under the receiver operating characteristic curve for the prognostic model performance was 0.76 95% CI, 0.66–0.85; pulmonary embolism severity index PESI and PESI + WBC count were 0.72 95% CI, 0.68–0.75 and 0.76 95% CI, 0.72–0.79, P 



Author: Jo, Jun Yeon; Lee, Mi Young; Lee, Jin Wook; Rho, Byung Hak; Choi, Won-Il

Source: https://archive.org/







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