Vol 29: Localized Thymic Amyloidosis Presenting with Myasthenia Gravis: Case Report.Report as inadecuate



 Vol 29: Localized Thymic Amyloidosis Presenting with Myasthenia Gravis: Case Report.


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This article is from Journal of Korean Medical Science, volume 29.AbstractA mediastinal mass was incidentally found on chest radiography in a 46-yr-old woman who had had myasthenia gravis MG for 2 months. Computed tomography revealed a 4-cm in size, well-defined, and lobulating mass with nodular calcification that was located in the thymus. Microscopically, the mass consisted of diffuse amorphous eosinophilic materials. These deposits exhibited apple-green birefringence under polarized light microscopy after Congo red staining. Immunohistochemical analysis revealed that they were positive for both kappa and lambda light chains and negative for amyloid A. A diagnosis of localized primary thymic amyloidosis was finally made. After thymectomy, the symptoms of MG were controlled with reduced corticosteroid requirements. Localized thymic amyloidosis associated with MG has not been reported to date.



Author: Son, Seung-Myoung; Lee, Yong-Moon; Kim, Si Wook; Lee, Ok-Jun

Source: https://archive.org/







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