Vol 9: Laparoscopic versus Open Hepatectomy with or without Synchronous Colectomy for Colorectal Liver Metastasis: A Meta-Analysis.Report as inadecuate



 Vol 9: Laparoscopic versus Open Hepatectomy with or without Synchronous Colectomy for Colorectal Liver Metastasis: A Meta-Analysis.


Vol 9: Laparoscopic versus Open Hepatectomy with or without Synchronous Colectomy for Colorectal Liver Metastasis: A Meta-Analysis. - Download this document for free, or read online. Document in PDF available to download.

Download or read this book online for free in PDF: Vol 9: Laparoscopic versus Open Hepatectomy with or without Synchronous Colectomy for Colorectal Liver Metastasis: A Meta-Analysis.
This article is from PLoS ONE, volume 9.AbstractBackground: To compare short-term and long-term results of colorectal patients undergoing laparoscopic and open hepatectomy. Moreover, outcomes of laparoscopic versus open procedures for simultaneous primary colorectal tumor and liver metastasis resection were compared. Methods: A systematic search was conducted in the PubMed and EmBase databases until Oct. 22. 2013 with no limits. Bibliographic citation management software EndNote X6 was used for extracted literature management. Quality assessment was performed according to a modification of the Newcastle-Ottawa Scale. The data were analyzed using Review Manager Version 5.1, and sensitivity analysis was performed by sequentially omitting each study. Results: Finally, 14 studies, including a total of 975 CLM colorectal liver metastasis patients, compared laparoscopic with open hepatectomy. 3 studies of them, including a total of 107 CLM patients, compared laparoscopic with open procedures for synchronous hepatectomy and colectomy. Laparoscopic hepatectomy was associated with a significantly less blood loss, shorter hospitalization time, and less operative transfusion rate. In addition, lower hospital morbidity rate OR = 0.57, 95%CI:0.42–0.78, P = 0.0005 and better R0 resection OR = 2.44, 95%CI:1.21–4.94, P = 0.01 were observed in laparoscopic hepatectomy. For long-term outcomes, there were no significant differences between two surgical procedures on recurrence and overall survival. In comparison of synchronous hepatectomy and colectomy, laparoscopic procedure displayed shorter hospitalization MD = −3.40, 95%CI:−4.37–2.44, P



Author: Wei, MingTian; He, YaZhou; Wang, JiaRong; Chen, Nan; Zhou, ZongGuang; Wang, ZiQiang

Source: https://archive.org/







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