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BMC Family Practice

, 10:63

First Online: 09 September 2009Received: 13 January 2009Accepted: 09 September 2009


BackgroundThe pathophysiology of upper gastrointestinal GI symptoms is still poorly understood. Psychological symptoms were found to be more common in patients with functional gastrointestinal complaints, but it is debated whether they are primarily linked to GI symptoms or rather represent motivations for health-care seeking. Purpose of our study was to compare co-morbidity, in particular psychological and social problems, between patients with and without upper GI symptoms. In addition, we investigated whether the prevalence of psychological and social problems is part of a broader pattern of illness related health care use.

MethodsPopulation based case control study based on the second Dutch National Survey of general practice conducted in 2001. Cases adults visiting their primary care physician PCP with upper GI symptoms and controls individuals not having any of these complaints, matched for gender, age, PCP-practice and ethnicity were compared. Main outcome measures were contact frequency, prevalence of somatic as well as psychosocial diagnoses, prescription rate of psychopharmacological agents, and referral rates. Data were analyzed using odds ratios, the Chi square test as well as multivariable logistic regression analysis.

ResultsData from 13,389 patients with upper GI symptoms and 13,389 control patients were analyzed. Patients with upper GI symptoms visited their PCP twice as frequently as controls 8.6 vs 4.4 times-year. Patients with upper GI symptoms presented not only more psychological and social problems, but also more other health problems to their PCP odds ratios ORs ranging from 1.37 to 3.45. Patients with upper GI symptoms more frequently used drugs of any ATC-class ORs ranging from 1.39 to 2.90, including psychotropic agents. The observed differences were less pronounced when we adjusted for non-attending control patients. In multivariate regression analysis, contact frequency and not psychological or social co-morbidity was strongest associated with patients suffering from upper GI symptoms.

ConclusionPatients with upper GI symptoms visit their PCP more frequently for problems of any organ system, including psychosocial problems. The relationship between upper GI symptoms and psychological problems is equivocal and may reflect increased health care demands in general.

List of abbreviationsATCAnatomical Therapeutic Chemical

CIconfidence interval

PCPprimary care physician

ICPCInternational Classification of Primary Care

NSAIDnon-steroid anti-inflammatory drug

ORodds ratio.

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Autor: Linda E Bröker - Gerard JB Hurenkamp - Gerben ter Riet - François G Schellevis - Hans G Grundmeijer - Henk C van Weer

Fuente: https://link.springer.com/

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