Rapid identification and antimicrobial susceptibility profiling of Gram-positive cocci in blood cultures with the Vitek 2 systemReportar como inadecuado




Rapid identification and antimicrobial susceptibility profiling of Gram-positive cocci in blood cultures with the Vitek 2 system - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

European Journal of Clinical Microbiology and Infectious Diseases

, 29:89

First Online: 10 November 2009Received: 05 June 2009Accepted: 03 October 2009

Abstract

Rapid identification and antimicrobial susceptibility profiling of the bacteria in blood cultures can result in clinical and financial benefits. Addition of saponin to the fluid from blood culture bottles promotes the recovery of the bacteria and thus may shorten the turnaround time of the microbiological analyses. In this study we compared the identification and susceptibility profiles of saponin-treated and untreated standard method blood cultures monomicrobial for Gram-positive cocci using Vitek 2. We concordantly identified 49 89% of 55 monobacterial cultures using the results with the standard method as reference. Complete categorical agreement between the susceptibility profiles with the new and the standard method was found for 26 53% of 49 isolates, while discrepancies were seen for 23 47% cultures. E-tests indicated that the new method resulted in a correct susceptibility profile for 8 35% of these 23 blood cultures. Therefore, 34 69% of 49 cultures showed a concordant-correct susceptibility profile for all antimicrobials with an overall error rate of 2.3%. Thus, addition of saponin to the fluid from blood culture bottles of the Bactec 9240 leads to the rapid results available ≥12 hours earlier and reliable identification and susceptibility profiling of Gram-positive cocci in blood cultures with Vitek 2.

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Autor: A. Lupetti - S. Barnini - B. Castagna - A.-L. Capria - P. H. Nibbering

Fuente: https://link.springer.com/



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