Tone burst-evoked otoacoustic emissions in neonates: normative dataReport as inadecuate

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BMC Ear, Nose and Throat Disorders

, 8:3

First Online: 17 April 2008Received: 29 November 2007Accepted: 17 April 2008


BackgroundTone-burst otoacoustic emissions TBOAEs have not been routinely studied in pediatric populations, although tone burst stimuli have greater frequency specificity compared with click sound stimuli. The present study aimed 1 to determine an appropriate stimulus level for neonatal TBOAE measurements when the stimulus center frequency was 1 kHz, 2 to explore the characteristics of 1 kHz TBOAEs in a neonatal population.

MethodsA total of 395 normal neonates 745 ears were recruited. The study consisted of two parts, reflecting the two study aims. Part I included 40 normal neonatal ears, and TBOAE measurement was performed at five stimulus levels in the range 60–80 dB peSPL, with 5 dB incremental steps. Part II investigated the characteristics of the 1 kHz TBOAE response in a large group of 705 neonatal ears, and provided clinical reference criteria based on these characteristics.

ResultsThe study provided a series of reference parameters for 1 kHz TBOAE measurement in neonates. Based on the results, a suggested stimulus level and reference criteria for 1 kHz TBOAE measures with neonates were established. In addition, time-frequency analysis of the data gave new insight into the energy distribution of the neonatal TBOAE response.

ConclusionTBOAE measures may be a useful method for investigating cochlear function at specific frequency ranges in neonates. However, further studies of both TBOAE time-frequency analysis and measurements in newborns are needed.

Electronic supplementary materialThe online version of this article doi:10.1186-1472-6815-8-3 contains supplementary material, which is available to authorized users.

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Author: Vicky Wei Zhang - Bradley McPherson - Zhi-Guo Zhang


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