The importance of rectal cancer MRI protocols on iInterpretation accuracyReportar como inadecuado

The importance of rectal cancer MRI protocols on iInterpretation accuracy - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

World Journal of Surgical Oncology

, 6:89

First Online: 20 August 2008Received: 27 May 2008Accepted: 20 August 2008


BackgroundMagnetic resonance imaging MRI is used for preoperative local staging in patients with rectal cancer. Our aim was to retrospectively study the effects of the imaging protocol on the staging accuracy.

Patients and methodsMR-examinations of 37 patients with locally advanced disease were divided into two groups; compliant and noncompliant, based on the imaging protocol, without knowledge of the histopathological results. A compliant rectal cancer imaging protocol was defined as including T2-weighted imaging in the sagittal and axial planes with supplementary coronal in low rectal tumors, alongside a high-resolution plane perpendicular to the rectum at the level of the primary tumor. Protocols not complying with these criteria were defined as noncompliant. Histopathological results were used as gold standard.

ResultsCompliant rectal imaging protocols showed significantly better correlation with histopathological results regarding assessment of anterior organ involvement sensitivity and specificity rates in compliant group were 86% and 94%, respectively vs. 50% and 33% in the noncompliant group. Compliant imaging protocols also used statistically significantly smaller voxel sizes and fewer number of MR sequences than the noncompliant protocols

ConclusionAppropriate MR imaging protocols enable more accurate local staging of locally advanced rectal tumors with less number of sequences and without intravenous gadolinium contrast agents.

AbbreviationsMRIMagnetic resonance imaging

TMETotal mesorectal excision

CRMCircumferential resection margin

T2-w imageT2 weighted image

FOVField of view

MDTMultidisciplinary team

PPVPositive predictive value

NPVNegative predictive value

TRRepetition Time

TEEcho Time

NEXnumber of excitations.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7819-6-89 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Chikako Suzuki - Michael R Torkzad - Soichi Tanaka - Gabriella Palmer - Johan Lindholm - Torbjörn Holm - Lennart Blomqvis


Documentos relacionados