Segmental resection of the duodenum for gastrointestinal stromal tumor GISTReportar como inadecuado

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World Journal of Surgical Oncology

, 6:105

First Online: 30 September 2008Received: 30 June 2008Accepted: 30 September 2008


BackgroundGastrointestinal stromal tumors GIST are the most frequent mesenchymal tumors of the gastrointestinal tract. The biological appearance of these tumors reaches from small lesions with benign appearance to aggressive sarcomas. Only 3–5% of GISTs are localized in the duodenum. There is a controversy, if duodenal GISTs should be treated by a duodenopancreatectomy or by a limited resection of the duodenum.

Case presentationA 29-year-old man presented with an acute upper gastrointestinal bleeding from a submucosal tumor located in the proximal part III of the duodenum, 3 cm distal of the papilla of Vater. After an emergency laparotomy with ligation of tumor-feeding vessels in a primary hospital, definitive surgical therapy was performed by partial resection of the duodenum with a duodenojejunostomy. Histology revealed a GIST with a diameter of 2.5 cm and <5 mitoses-50 high power fields, indicating a low risk of malignancy. Therefore no adjuvant therapy with Imatinib was initiated.

ConclusionGISTs of the duodenum are a rare cause of upper gastrointestinal bleeding. Partial resection of the duodenum is a warranted alternative to a duodenopancreatectomy, as this procedure has a lower operative morbidity, while providing comparable oncological results.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7819-6-105 contains supplementary material, which is available to authorized users.

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Autor: Rudolf Mennigen - Heiner H Wolters - Bernd Schulte - Friedrich W Pelster


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