Single-day therapy: an expert opinion on a recent development for the episodic treatment of recurrent genital herpesReportar como inadecuado




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Archives of Gynecology and Obstetrics

, Volume 275, Issue 1, pp 1–3

First Online: 07 September 2006Received: 21 July 2006Accepted: 07 August 2006

Abstract

One common method for treating recurrent genital herpes outbreaks is 3–5 day episodic therapy with nucleoside analogues. However, since maximum viral replication occurs within 24 h after the onset of symptoms, short-term patient-initiated episodic therapy started at prodromal onset or at the first appearance of lesions in patients without a prodrome may represent an important option. In a recent randomized trial, single-day famciclovir treatment decreased lesion healing time and the duration of pain and other symptoms by approximately 2 days compared to placebo, and prevented progression to a full outbreak in almost one in four patients. Because single-day treatment is more convenient than traditional therapies, it may lead to improved patient compliance and better overall management of recurrent genital herpes outbreaks.

KeywordsSingle-day famciclovir Genital herpes Patient-initiated episodic therapy  Download fulltext PDF



Autor: Stephen Tyring - Gary Richwald - Kamal Hamed

Fuente: https://link.springer.com/







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