Time trends of chest pain symptoms and health related quality of life in coronary artery diseaseReportar como inadecuado

Time trends of chest pain symptoms and health related quality of life in coronary artery disease - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Health and Quality of Life Outcomes

, 5:13

First Online: 06 March 2007Received: 06 December 2006Accepted: 06 March 2007


BackgroundThere is at present a lack of knowledge of time trends in health related quality of life HRQL in common patients with coronary artery disease CAD treated in ordinary care. The objective of this study is to assess and compare time trends of health related quality of life HRQL and chest pain in patients with coronary artery disease.

Methods253 consecutive CAD patients in Stockholm County, Sweden – 197 males-56 females; 60 ± 8 years – were followed during two years. Perceived chest pain symptoms and three global assessments of HRQL were assessed at baseline, after one and after two years. EuroQol-5 dimension EQ-5D with a predefined focus on function and symptoms; the broader tapping global estimates of HRQL; EuroQol VAS EQ-VAS and Cardiac Health Profile CHP were used. Chest pain was ranked according to Canadian Cardiovascular Society CCS. Change in HRQL was analysed by a repeated measurements ANOVA and chest pain symptoms were analysed by Friedman non-parametric ANOVA.

ResultsPerceived chest pain decreased during the two years p < 0.00022; CCS 0: 41–51%; CCS 1: 19–15%; CCS 2: 31–27%; CCS 3: 5–4% and CCS 4: 4–2%. By contrast, HRQL did not change: EQ-5D: 0.76 CI 0.73–0.79 -0.78 CI 0.75–0.81, EQ-VAS: 0.68 CI 0.66–0.71-0.68 CI 0.65–0.71 and CHP: 0.66 CI 0.64–0.69 -0.66 CI 0.64–0.69.

ConclusionHRQL did not increase despite a reduction in the severity of chest pain during two years. This implies that the major part of HRQL in these consecutive ordinary patients with CAD is unresponsive to change in chest pain symptoms.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7525-5-13 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Autor: Anna Kiessling - Peter Henriksson

Fuente: https://link.springer.com/

Documentos relacionados