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Molecular Cancer

, 6:78

First Online: 04 December 2007Received: 19 November 2007Accepted: 04 December 2007

Abstract

Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after appearance and that a memory with maturated weapons exists, if the organism is re-infected by the same particle. For malignant cells, however, the immune response seems to be restricted to innate immunity, because at least for the humoral response, all so far detected tumor-specific antibodies belong to the natural immunity. In this review we try to explain why malignant cells might be -too sweet- to induce a memory.

Electronic supplementary materialThe online version of this article doi:10.1186-1476-4598-6-78 contains supplementary material, which is available to authorized users.

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Autor: H Peter Vollmers - Stephanie Brändlein

Fuente: https://link.springer.com/







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