Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additiveReportar como inadecuado




Initial in vitro screening approach to investigate the potential health and environmental hazards of Envirox™ – a nanoparticulate cerium oxide diesel fuel additive - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Particle and Fibre Toxicology

, 4:12

First Online: 05 December 2007Received: 20 March 2007Accepted: 05 December 2007

Abstract

Nanotechnology is the new industrial revolution of the 21st Century as the various processes lead to radical improvements in medicine, manufacturing, energy production, land remediation, information technology and many other everyday products and applications. With this revolution however, there are undoubted concerns for health, safety and the environment which arise from the unique nature of materials and processes at the nanometre scale.

The in vitro assays used in the screening strategy are all validated, internationally accepted protocols and provide a useful indication of potential toxicity of a chemical as a result of effects on various toxicological endpoints such as local site of contact dermal irritation, general cytotoxicity and mutagenicity.

The initial in vitro screening strategy described in this paper to investigate the potential health implications, if any, which may arise following exposure to one specific application of nanoparticulate cerium oxide used as a diesel fuel borne catalyst, reflects a precautionary approach and the results will inform judgement on how best to proceed to ensure safe use.

Electronic supplementary materialThe online version of this article doi:10.1186-1743-8977-4-12 contains supplementary material, which is available to authorized users.

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Autor: Barry Park - Patricia Martin - Chris Harris - Robert Guest - Andrew Whittingham - Peter Jenkinson - John Handley

Fuente: https://link.springer.com/



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