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BMC Medical Informatics and Decision Making

, 6:25

First Online: 20 June 2006Received: 08 March 2006Accepted: 20 June 2006

Abstract

BackgroundThe Cancer Biomedical Informatics Grid caBIG™ is a network of individuals and institutions, creating a world wide web of cancer research. An important aspect of this informatics effort is the development of consistent practices for data standards development, using a multi-tier approach that facilitates semantic interoperability of systems. The semantic tiers include 1 information models, 2 common data elements, and 3 controlled terminologies and ontologies. The College of American Pathologists CAP cancer protocols and checklists are an important reporting standard in pathology, for which no complete electronic data standard is currently available.

MethodsIn this manuscript, we provide a case study of Cancer Common Ontologic Representation Environment caCORE data standard implementation of the CAP cancer protocols and checklists model – an existing and complex paper based standard. We illustrate the basic principles, goals and methodology for developing caBIG™ models.

ResultsUsing this example, we describe the process required to develop the model, the technologies and data standards on which the process and models are based, and the results of the modeling effort. We address difficulties we encountered and modifications to caCORE that will address these problems. In addition, we describe four ongoing development projects that will use the emerging CAP data standards to achieve integration of tissue banking and laboratory information systems.

ConclusionThe CAP cancer checklists can be used as the basis for an electronic data standard in pathology using the caBIG™ semantic modeling methodology.

Electronic supplementary materialThe online version of this article doi:10.1186-1472-6947-6-25 contains supplementary material, which is available to authorized users.

Ram Chilukuri, George A Komatsoulis, Nicholas Sioutos, Denise B Warzel, Lawrence W Wright contributed equally to this work.

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Autor: Jonathan Tobias - Ram Chilukuri - George A Komatsoulis - Sambit Mohanty - Nicholas Sioutos - Denise B Warzel - Lawrence W

Fuente: https://link.springer.com/



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