Granulomatous meningoencephalomyelitis in dogs: A reviewReportar como inadecuado

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Irish Veterinary Journal

, 58:86

First Online: 01 February 2005


Granulomatous meningoencephalomyelitis GME is an inflammatory disease of the central nervous system in dogs that is characterised by focal or disseminated granulomatous lesions within the brain and-or spinal cord, non-suppurative meningitis and perivascular mononuclear cuffing. The aetiology of the disease remains unknown, although an immune-mediated cause is suspected. This article reviewed the typical history, clinical signs and pathology of the condition along with current opinions on pathogenesis. The potential differential diagnoses for the disease were discussed along with current treatment options.

KeywordsDog Brain Granulomatous meningoencephalomyelitis AbbreviationsCTcomputed tomography

CDVcanine distemper virus

CNcranial nerve

CNScentral nervous system

CSFcerebrospinal fluid

DTHdelayed-type hypersensitivity

GMEgranulomatous meningoencephalomyelitis

MHCmajor histocompatibility

MRImagnetic resonance imaging

PCRpolymerase chain reaction

UMNupper motor neuron.

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Autor: Emma J. O-Neill - Darren Merrett - Boyd Jones


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