Prevalence of ultrasonography proved polycystic ovaries in North Indian women with type 2 diabetes mellitusReportar como inadecuado

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Reproductive Biology and Endocrinology

, 3:35

First Online: 11 August 2005Received: 06 April 2005Accepted: 11 August 2005


BackgroundPolycystic ovaries PCO and their clinical expression the polycystic ovary syndrome PCOS as well as type 2 diabetes mellitus T2DM are common medical conditions linked through insulin resistance. We studied the prevalence of PCO and PCOS in women with diet and-or oral hypoglycemic treated T2DM and non-diabetic control women.

DesignProspective study.

MethodsOne hundred and five reproductive age group women with diet and -or oral hypoglycemic treated T2DM were the subjects of the study. Sixty age-matched non-diabetic women served as controls. Transabdominal ultrasonographic assessment of the ovaries was used to diagnose PCO. Clinical, biochemical and hormonal parameters were also noted.

ResultsUltrasonographic prevalence of PCO was higher in women with diabetes than in non-diabetic subjects 61.0% vs. 36.7%, P < 0.003 whereas that of PCOS was 37.1% in diabetic subjects and 25% in non-diabetic controls P > 0.1. Diabetic women with PCO had diabetes of significantly longer duration than those without PCO 4.19±2.0 versus 2.9±1.6 yrs; p < 0.05. Among both diabetic and non-diabetic women, those with PCO had significantly higher plasma LH, LH-FSH ratio, total testosterone and androstenedione levels.

ConclusionThis study demonstrates a higher prevalence of PCO in women with T2DM as compared to non-diabetic subjects.

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Autor: Abdul H Zargar - Vipin K Gupta - Arshad I Wani - Shariq R Masoodi - Mir I Bashir - Bashir A Laway - Mohammad A Ganie


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