Biomechanics of porcine renal arteries and role of axial stretch.Report as inadecuate

Biomechanics of porcine renal arteries and role of axial stretch. - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 CIS-ENSMSE - Centre Ingénierie et Santé 2 IFRESIS-ENSMSE - Institut Fédératif de Recherche en Sciences et Ingénierie de la Santé 3 LGF-ENSMSE - UMR 5307 - Laboratoire Georges Friedel 4 STBio-ENSMSE - Surfaces et Tissus Biologiques 5 DME-USC - Department of Mechanical Engineering 6 DCBA - Department of Cell Biology and Anatomy

Abstract : It is known that arteries experience significant axial stretches in vivo. Several authors have shown that the axial force needed to maintain an artery at its in vivo axial stretch does not change with transient cyclical pressurization over normal ranges. However, the axial force phenomenon of arteries has never been explained with microstructural considerations. In this paper we propose a simple biomechanical model to relate the specific axial force phenomenon of arteries to the predicted load-dependent average collagen fiber orientation. It is shown that a the model correctly predicts the authors- experimentally measured biaxial behavior of pig renal arteries and b the model predictions are in agreement with additional experimental results reported in the literature. Finally, we discuss the implications of the model for collagen fiber orientation and deposition in arteries.

keyword : pig renal arteries axial stretches in vivo modelling collagen fiber orientation

Author: Stéphane Avril - Pierre Badel - Mohamed Gabr - Michael Sutton - Susan Lessner -



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