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Health and Quality of Life Outcomes

, 2:8

First Online: 12 February 2004Received: 03 November 2003Accepted: 12 February 2004


BackgroundThis paper describes the development of a new quality of life instrument in advanced cancer patients receiving palliative care.

MethodsThe Palliative Care Quality of Life Instrument incorporates six multi-item and one single-item scale. The questionnaire was completed at baseline and one-week after. The final sample consisted of 120 patients.

ResultsThe average time required to complete the questionnaire, in both time points, was approximately 8 minutes. All multi-item scales met the minimal standards for reliability Cronbach-s alpha coefficient ≥.70 either before or during palliative treatment. Test-retest reliability in terms of Spearman-rho coefficient was also satisfactory p < 0.05. Validity was demonstrated by inter-item correlations, comparisons with ECOG performance status, factor analysis, criterion-related validation, and correlations with the Assessment of Quality of Life in Palliative Care Instrument AQEL, and the European Organisation for Research and Treatment of Cancer EORTC Core Quality of Life Questionnaire QLQ-C30, version 3.0.

ConclusionThe PQLI is a reliable and valid measure for the assessment of quality of life in patients with advanced stage cancer.

Electronic supplementary materialThe online version of this article doi:10.1186-1477-7525-2-8 contains supplementary material, which is available to authorized users.

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Autor: Kyriaki Mystakidou - Eleni Tsilika - Vassilios Kouloulias - Efi Parpa - Emmanuela Katsouda - John Kouvaris - Lambros Vlahos


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