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* Corresponding author 1 CESP - Centre de recherche en épidémiologie et santé des populations 2 Department of Child Psychiatry 3 GRIP - Groupe de Recherche en Inadaptation Psychosociale 4 Epidémiologie et Biostatistique Bordeaux 5 Child Psychiatry 6 Troubles du comportement alimentaire de l-adolescent

Abstract : BACKGROUND: One possible risk marker of later internalising symptoms is poor sleep, which is a problem for up to 40% of children. The present study investigated whether prior sleep problems could predict internalising symptoms over a period of 18 years of follow-up. METHODS: The study sample included 1503 French young adults from the TEMPO cohort mean age=28.8±3.6 years whose parents participate in the GAZEL cohort study. All TEMPO participants previously took part in a study of children-s mental health and behaviour in 1991 mean age=10.3±3.6 years and 1999 mean age=18.8±3.6 years. Sleep problems and internalising symptoms depression, anxiety, somatic complaints were assessed three times 1991, 1999, 2009 using the Achenbach System of Empirically Based Assessment ASEBA questionnaire. The association between sleep problems in 1991 and trajectories of internalising problems from 1991 to 2009 was tested in a multinomial logistic regression framework, controlling for sex, age, baseline temperament, behavioural problems and stressful life events, as well as family income, and parental history of depression. RESULTS: We identified four trajectories of internalising symptoms: high-persistent 2.5%, high-decreasing 11.4%, low-increasing 11.6%, and low-persistent 74.5%. After controlling for covariates, compared to participants who did not have sleep problems in 1991, those who did were 4.51 times 95% CI=1.54-13.19, P=.006 more likely to have high-persistent internalising symptoms and 3.69 times 95% CI=2.00-6.82, P

Autor: Evelyne Touchette - Aude Chollet - Cédric Galéra - Eric Fombonne - Bruno Falissard - Michel Boivin - Maria Melchior -



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