Predictive factors of HTLV1-HIV coinfections in French Guiana.Report as inadecuate

Predictive factors of HTLV1-HIV coinfections in French Guiana. - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 Departement des Maladies infectieuses 2 COREVIH Guyane - Coordination Régionale de la lutte contre le Virus de L-Immunodéficience Humaine 3 Epidémiologie des parasitoses et mycoses tropicales

Abstract : French Guiana, the French territory most affected by human immunodeficiency virus HIV 1.3% of pregnant women, is also endemic for human T lymphotropic virus 1 HTLV1. The objective of this study was to determine if the HTLV1-HIV coinfected patients had particular characteristics. All HIV-infected patients having a computerized medical file containing an HTLV1 serology were included: there were 1,333 HIV monoinfections and 76 HTLV1-VIH coinfections. The prevalence of HTLV1-HIV coinfections was 5.39%. Women odds ratio OR = 1.911.13-3.24, subjects > 40 years of age, and patients of Surinamese origin OR = 2.65 1.25-5.61 were overrepresented among the coinfected. CD4 count at the time of diagnosis and viral loads were higher among coinfected patients. The clinical stage was not significantly different between the two groups. The number of CD4 cells was not higher among the coinfected, unlike most reports from the literature. Prevalence of HTLV1 among HIV-infected patients is high in French Guiana, and physicians seem to omit the prescription of serology for this potentially serious coinfection.

Author: Elise Gouhier - Emilie Gaubert-Maréchal - Philippe Abboud - Pierre Couppié - Mathieu Nacher -



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