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Alessandro Finkelsztejn ; Sidney Gomes ; Yára Dadalti Fragoso ;Dementia & Neuropsychologia 2012, 6 1

Autor: Maria Fernanda Mendes

Fuente: http://www.redalyc.org/articulo.oa?id=339529036007


Introducción



Dementia & Neuropsychologia ISSN: 1980-5764 demneuropsy@uol.com.br Associação Neurologia Cognitiva e do Comportamento Brasil Mendes, Maria Fernanda; Finkelsztejn, Alessandro; Gomes, Sidney; Dadalti Fragoso, Yára Early and severe cognitive impairment in multiple sclerosis Dementia & Neuropsychologia, vol.
6, núm.
1, enero-marzo, 2012, pp.
48-52 Associação Neurologia Cognitiva e do Comportamento São Paulo, Brasil Available in: http:--www.redalyc.org-articulo.oa?id=339529036007 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative Original Article Dement Neuropsychol 2012 March;6(1):48-52 Early and severe cognitive impairment in multiple sclerosis Maria Fernanda Mendes1, Alessandro Finkelsztejn2, Sidney Gomes3, Yára Dadalti Fragoso4 ABSTRACT.
Objectives: To report on four new cases of severe cognitive impairment in the early stages of multiple sclerosis (MS) and to review data on the subject since few cases have been reported worldwide.
Methods: Retrospective evaluation of medical records of patients with severe cognitive impairment within the first five years of MS diagnosis.
Results on neuropsychological tests and magnetic resonance imaging (MRI) were disclosed.
Results: Four patients from different Brazilian neurological departments in Brazil were evaluated, all presenting with severe cognitive dysfunction classified as rapidly developing dementia.
MRI images showed severe brain atrophy and basal ganglia lesions in all patients.
Conclusions: Although rare, severe cognitive impairment in MS represents an important disability and may ultimately constitute another form of the disease. Key words: multiple sclerosis, cognition, dementia, basal ganglia, brain atrophy. COMPROMETIMENTO COGNITIVO PRECOCE E GRAVE NA ESCLEROSE MÚLTIP...





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