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Eneida Mioshi ; Belinda Yew ; John R. Hodges ; Michael Hornberger ;Dementia & Neuropsychologia 2012, 6 1

Autor: Christopher Go

Fuente: http://www.redalyc.org/articulo.oa?id=339529036003


Introducción



Dementia & Neuropsychologia ISSN: 1980-5764 demneuropsy@uol.com.br Associação Neurologia Cognitiva e do Comportamento Brasil Go, Christopher; Mioshi, Eneida; Yew, Belinda; Hodges, John R.; Hornberger, Michael Neural correlates of behavioural symptoms in behavioural variant frontotemporal dementia and Alzheimer’s disease.
Employment of a visual MRI rating scale Dementia & Neuropsychologia, vol.
6, núm.
1, enero-marzo, 2012, pp.
12-17 Associação Neurologia Cognitiva e do Comportamento São Paulo, Brasil Available in: http:--www.redalyc.org-articulo.oa?id=339529036003 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative Dement Neuropsychol 2012 March;6(1):12-17 Original Article Neural correlates of behavioural symptoms in behavioural variant frontotemporal dementia and Alzheimer’s disease Employment of a visual MRI rating scale Christopher Go1,2, Eneida Mioshi1,2, Belinda Yew1, John R.
Hodges1,2, Michael Hornberger1,2 ABSTRACT.
Frontotemporal dementia (FTD) patients often present with severe behavioural disturbances and concomitant lack of insight.
The underlying neural correlates of these disturbances are mostly attributed to prefrontal cortex dysfunction, but are still poorly understood.
Objectives: The current study explores whether a simple visual magnetic resonance imaging (MRI) rating scale in combination with the Frontal System Behaviour Scale (FrSBe) can be used to identify the prefrontal correlates of behavioural symptoms in behavioural variant frontotemporal dementia (bvFTD) and Alzheimer’s disease (AD). Methods: Forty-eight patients with a clinical diagnosis of bvFTD and AD participated in the study.
Their behavioural profiles were assessed using the Frontal System Behaviour Scale (FrSBe) and cross-correlated to...





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