Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism.Reportar como inadecuado




Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism. - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

* Corresponding author 1 PRC - Physiologie de la reproduction et des comportements Nouzilly 2 IGDR - Institut de Génétique et Développement de Rennes

Abstract : In mammals, the Tribbles family includes widely expressed serine-threonine kinase-like proteins TRIB1, TRIB2 and TRIB3 that are involved in multiple biological processes including cell proliferation and fatty acid FA metabolism. Our recent studies highlighted the importance of FA metabolism in cumulus cells CC during oocyte maturation in vertebrates and reported a higher TRIB1 expression in CC surrounding in vivo mature oocytes as compared to immature ooocytes in mice and cows. The objective was to investigate Tribbles expression patterns in bovine CC during in vitro maturation IVM and to examine their roles in the cumulus-oocyte complex.





Autor: Daphné Brisard - Franck Chesnel - S. Elis - A. Desmarchais - L. Sanchez-Lazo - M. Chasles - V. Maillard - Svetlana Uzbekova -

Fuente: https://hal.archives-ouvertes.fr/



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