Superior Vena Cava Syndrome. From the Bronchus to the VesselReport as inadecuate

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Diagnostic and Therapeutic Endoscopy - Volume 4 1997, Issue 2, Pages 83-93


Division of Pneumology, Department of Internal Medicine I, Medical School (Charité), Humboldt-University, Berlin, Germany

Division of Interventional Radiology, Department of Radiology, Medical School (Charité), Humboldt-University, Berlin, Germany

Received 26 December 1996; Revised 10 March 1997; Accepted 8 May 1997

Copyright © 1997 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper addresses the diagnosis and management of superior vena cava syndrome(SVCS) due to malignant intrathoracic tumours. Diagnosis of SVCS is usually establishedby bedside examination. Chest X-ray and computed tomography may be helpful, but thecavography remains the “gold-standard”. Other imaging techniques (MRI, nuclear flowstudies) are more of scientific interest. Bronchoscopy helps to evaluate the risk of pulmonarycomplications and endoscopic procedures often lead to histological findings. In thetreatment of malignant SVCS surgery, radiotherapy, and chemotherapy have been successfullyused. The placement of a vascular stent might be an additional or alternative possibility.There are no conclusive indication criteria and no conclusive regimen concerningpost-stenting anticoagulation. From all reported results and published papers we draw theconclusion that the immediate effects of stent implantation and the long-term results oftumour-specific therapy are complementary to one another. The stent dilates the localvenous stenosis while tumour-specific therapy has a general effect on the vascular andrespiratory situation in a multi-therapy concept.

Author: C. Witt, B. Schmidt, A. C. Borges, W. Doerffel, G. Baumann, and P. Romaniuk



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