Is Hydrogen Breath Test with Lactulose Feasible for Measuring Gastrocecal Transit in Critically Ill Children Pilot Study about Modification of the TechniqueReportar como inadecuado




Is Hydrogen Breath Test with Lactulose Feasible for Measuring Gastrocecal Transit in Critically Ill Children Pilot Study about Modification of the Technique - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

BioMed Research International - Volume 2017 2017, Article ID 5878659, 6 pages - https:-doi.org-10.1155-2017-5878659

Research Article

Pediatric Intensive Care Department, Gregorio Marañón General University Hospital, School of Medicine, Complutense University of Madrid, Gregorio Marañón Health Research Institute, Mother-Child Health and Development Network Red SAMID of Carlos III Health Institute, Spain

Gastroenterology Unit, Gregorio Marañón General University Hospital, Complutense University of Madrid, Spain

Correspondence should be addressed to J. López and J. López-Herce

Received 2 September 2016; Revised 18 December 2016; Accepted 28 December 2016; Published 26 January 2017

Academic Editor: Toshimi Chiba

Copyright © 2017 J. López et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Gastrocecal transit time GCTT can be measured by exhaled hydrogen after lactulose intake lactulose-eH2 test. The objectives were to assess whether it is possible to carry out this test in critically ill children with and without mechanical ventilation MV and to analyze whether the results are consistent with clinical findings. Methods. Patients admitted to the Pediatric Intensive Care Unit PICU for more than 3 days were included. Those with gastrointestinal disease prior to admission were excluded. A modified technique to obtain eH2 from the ventilator tubes was performed. Results. Sixteen patients 37.5% boys with a median age of 19 5–86.5 months were included. Five patients 31.2% were breathing spontaneously but lactulose-eH2 test could not be performed while it could be performed successfully in the 11 patients with MV. Seven patients 63.3% did not show an eH2 peak. The other 4 showed a median time of 130 min 78.7–278.7 min from lactulose intake to a 10 ppm eH2 peak. Children with an eH2 peak had intestinal movements earlier 6.5 1.5–38.5 versus 44 24–72 hours . Conclusion. Although the designed adaption is useful for collecting breath samples, lactulose-eH2 test may not be useful for measuring GCTT in critically ill children.





Autor: J. López, C. Sánchez, S. N. Fernández, R. González, M. J. Solana, J. Urbano, M. Tolín, and J. López-Herce

Fuente: https://www.hindawi.com/



DESCARGAR PDF




Documentos relacionados