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BioMed Research International - Volume 2014 2014, Article ID 243056, 6 pages -

Review Article

Department of Medicine and Health Sciences, University of Molise, via De Sanctis, 86100 Campobasso, Italy

Department of Ophthalmology, University of Brescia, Piazzale Spedali, 25123 Brescia, Italy

Department of Ophthalmology, G. Moscati Hospital, Contrada Amoretta, 83100 Avellino, Italy

Department of Naples, INAIL ex ISPESL Settore Ricerca, Certificazione Verifica, 80143 Naples, Italy

Department of Ophthalmology, Federico II University, Via Pansini, 80131 Naples, Italy

Department of Bioscience and Territory, University of Molise, Contrada Conte Lappone, Pesche, 86090 Isernia, Italy

Received 11 February 2014; Revised 3 June 2014; Accepted 16 June 2014; Published 15 July 2014

Academic Editor: Kenneth Li

Copyright © 2014 Ciro Costagliola et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The importance of gravitational instability in determining the emulsification of vitreal tamponades is discussed. Theoretical results and numerical simulations indicate that the spontaneous formation of water-silicon oil is a rare event and that the very low concentration of surface active agents cannot justify the systematic formation of emulsions. The gravitational instabilities seem to play the main role. Our theoretical results seem in agreement with the experimental evidences; furthermore they indicate a future research line for the improvement of endotamponades. Indeed, the use of biodegradable antifoam may avoid the formation of bubbles and delay the formation of emulsions.

Autor: Ciro Costagliola, Francesco Semeraro, Roberto dell’Omo, Lucio Zeppa, Gennaro Bufalo, Michele Cardone, Mario Romano, and L



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