Multiobjective patient-specific estimation of a coronary circulation model for triple vessel disease.Reportar como inadecuado




Multiobjective patient-specific estimation of a coronary circulation model for triple vessel disease. - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

* Corresponding author 1 LTSI - Laboratoire Traitement du Signal et de l-Image 2 BIM - Biomécanique et génie biomédical 3 Service de chirurgie thoracique cardiaque et vasculaire Rennes

Abstract : Computational models can help understand the hemodynamics of the coronary circulation, which is of the upmost importance to help clinicians before, during and after a coronary artery bypass graft surgery. In this paper, we propose a multiobjective optimization method for parameter estimation of a computational model representing the coronary circulation on patients with a triple vessel disease. This estimation was not based on any assumption regarding the development of the collateral circulation, like in previous works. Indeed, the collateral development of a given patient is estimated through the model parameters. Parameter estimation was performed using clinical data from three patients, obtained before and during an off-pump coronary artery bypass graft surgery CABG. Results showed a better performance when comparing the simulation with clinical data, since the total error estimation for three patients was reduced by 40 ± 22%. Moreover, the proposed method provides new insight regarding the heterogeneous configuration of the alternative collateral vessels.





Autor: David Ojeda - Virginie Le Rolle - Agnes Drochon - Majid Harmouche - Herve Corbineau - Jean-Phillipe Verhoye - Alfredo Hernandez -

Fuente: https://hal.archives-ouvertes.fr/



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