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ISRN MicrobiologyVolume 2012 2012, Article ID 658470, 5 pages

Research ArticleDepartment of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

Received 21 August 2012; Accepted 6 September 2012

Academic Editors: G. Alexandre and M. Labrenz

Copyright © 2012 Duredoh Freeman George et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Nosocomial infections are infections acquired by a patient as a result of treatment in a hospital or healthcare service providing center and symptoms occurs within a short period of hospitalization. The study was to determine the antibiotic resistance patterns of Escherichia coli isolated from Kumasi-South, Tafo and Suntreso Hospitals, Kumasi, Ghana. Total of 600 swabs samples from the hospitals were collected between January and June, 2010. The isolates were identified using morphological and biochemical means. A total of 97 E. coli isolates were obtained from the hospitals. Beds in hospital wards had the highest number of E. coli strains 53.6%, followed by floors 20.6% while drainages had the least isolates 3.1%. Majority of the E. coli isolates 90.7% exhibited resistance to ampicillin while 6.2 and 3.1% showed intermediate and sensitive respectively. Co-trimoxazole, 78.4% of the isolates were resistant while 9.3 and 12.4% exhibited intermediate and sensitive responses respectively. E. coli isolates 28.6 to 46.4% were resistant to gentamicin, ciprofloxacin and ceftriaxone while 14.4 to 47.4% gave intermediate responses. Most isolates 80.4% exhibited multi-drug resistance. There is a need to observe proper personal hygiene, use of effective disinfectants and proper disposal of contaminated-pathogenic materials in these hospitals to control nosocomial infections.

Autor: Duredoh Freeman George, Stephen Yao Gbedema, Christian Agyare, Francis Adu, Vivian Etsiapa Boamah, Adelaide Ama Tawiah, and



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