A Case Report on the Progression of Myeloid Sarcoma to Form Multiple Metastatic Deposits without Developing Acute Myeloid LeukaemiaReportar como inadecuado




A Case Report on the Progression of Myeloid Sarcoma to Form Multiple Metastatic Deposits without Developing Acute Myeloid Leukaemia - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Case Reports in Hematology - Volume 2015 2015, Article ID 162154, 5 pages -

Case Report

Northern Deanery, 45 Briarfield Road, Gosforth, Newcastle upon Tyne NE3 3UH, UK

City Hospitals Sunderland and St. Benedict’s Hospice, St. Benedict’s Way, Ryhope SR2 0NY, UK

City Hospitals Sunderland, Sunderland Royal Hospital, Kayll Road, Sunderland SR4 7TP, UK

Received 31 July 2015; Accepted 19 September 2015

Academic Editor: Yusuke Shiozawa

Copyright © 2015 Sunita Kohli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Myeloid sarcomas MS are rare tumours occurring at extramedullary sites. They are usually associated with other haematology disorders such as acute myeloid leukaemia, myelodysplastic syndrome, and chronic myeloproliferative neoplasms. They frequently occur with a diagnosis of acute myeloid leukaemia AML or with relapse of preexisting disease. Patients with myeloid sarcomas without history or evidence of myeloid leukaemia typically progress to form AML. Case Presentation. A case report of a patient diagnosed with an isolated myeloid sarcoma that rarely did not transform to AML but instead spread to form multiple myeloid sarcomas throughout the body. Discussion. This case identifies the risk of metastatic spread of these tumours rather than the development of AML which is poorly documented in the literature, due to the rarity of cases, and may be significant in the investigation and management of isolated myeloid sarcomas. This case highlights the need for clinicians to consider repeat cross-sectional imaging to investigate unexplained clinical decline or symptoms, when there is no sign of AML progression and to consider radiotherapy treatment early.





Autor: Sunita Kohli, Mark Lee, and Scott Marshall

Fuente: https://www.hindawi.com/



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