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HPB Surgery - Volume 3 1991, Issue 4, Pages 235-249



Department of Surgical Oncology, National Cancer Center Hospital, Tokyo, Japan

Department of Surgical Oncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104, Japan

Received 1 July 1990; Accepted 1 July 1990

Copyright © 1991 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The number of hepatectomies has increased greatly in recent years. Surgery for hepatocellularcarcinoma HCC in the normal liver has not increased. However, the increase in numbers ofhepatectomies for HCC associated with liver cirrhosis is remarkable. More than 80% of our hepatectomycases were cirrhotic and about 80% of these cirrhotic cases had HCCs 5cm or less in diameter. Theoperative mortality rate has improved in the latter half of this series, from 10.1% 9-89 to 1.5% 5-338,in spite of an increase in cases with poor liver function. This corresponds to a decrease in the mean valueof the annual operative blood loss. The survival rates after hepatectomy for all cases n = 378 were40.6% ± 6.6 % ± SE for 5 year and 22.7% ± 5.3 for 10 year at the end of 1988. A difference of the5-year survival rate between the patients operated on before 1981 n = 78, 25.6% ± 4.9 and after 1982n = 300, 46.1% ± 4.8 was observed p<0.05. Because the cancer-free survival rates of the patientsoperated on in the two periods, before 1981 and after 1982, were almost the same, the recentimprovement of the survival rates seems to be due to a prolongation of survival time after recurrence.





Autor: Susumu Yamasaki, Masatoshi Makuuchi, and Hiroshi Hasegawa

Fuente: https://www.hindawi.com/



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