Suicide by self-injection of chlormequat trademark C5SUN®Report as inadecuate

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* Corresponding author 1 Institut national de criminalistique et de criminologie 2 Foie, métabolismes et cancer 3 CHU Pontchaillou Rennes

Abstract : Chlormequat is a quaternary ammonium used as plant growth regulating agent. We report here the first suicide case involving a 45 year-old farmer man who intentionally self-injected C5SUN®, containing chlormequat and choline. An original liquid chromatography high resolution mass spectrometry method LC-HR-MS, using an hybrid quadrupole-orbitrap mass spectrometer, was developed for qualitative and quantitative analysis of chlormequat in different biological matrices. Toxicological analyses of post-mortem samples highlighted the presence of chlormequat in the blood 2.25 mg-L and the urine 4.45 mg-L, in addition to ethanol impregnation blood 1.15 g-L. The route of administration subcutaneous injection was confirmed by the detection of chlormequat in the abdominal fat sample chlormequat: 10.04 mg-g taken from the traumatic injury location, as well as in the syringe found at the death scene, close to the victim-s body. Based on the results of these postmortem investigations, the cause of death was determined to be consecutive to cardiac dysrhythmia and cardiac arrest following chlormequat self-injection

Keywords : Chlormequat CCC Poisoning C5SUN® Suicide

Author: Yacine Boumrah - Thomas Gicquel - Chloé Hugbart - Alain Baert - Isabelle Morel - Renaud Bouvet -



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