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Case Reports in Nephrology - Volume 2014 2014, Article ID 865471, 4 pages -

Case Report

Department of Renal Medicine, Central Manchester NHS Foundation Trust, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK

Department of Clinical Virology, Central Manchester NHS Foundation Trust, Manchester M13 9WL, UK

Department of Hepatology, Central Manchester NHS Foundation Trust, Manchester M13 9WL, UK

Department of Pathology, Central Manchester NHS Foundation Trust, Manchester M13 9WL, UK

Blood Borne Virus Unit, MS-Colindale, Public Health England, London NW9 5EQ, UK

Received 18 May 2014; Accepted 29 July 2014; Published 11 September 2014

Academic Editor: Raoul Bergner

Copyright © 2014 Diana Vassallo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An asymptomatic 35-year-old renal transplant recipient was noted to have deranged liver function tests. Liver biopsy revealed a portal inflammatory process with mild lobular activity and portal fibrous expansion, consistent with a virally mediated process. An extensive viral screen confirmed infection with Hepatitis E virus genotype 3 HEV-3. There is increased awareness about locally acquired Hepatitis E virus HEV infection in the transplant population in the UK. The important implications of this infection are becoming more apparent as progression to liver cirrhosis can occur. However, the incidence, natural history, and treatment of HEV infection in the transplant population are not well established. This report illustrates a case of delayed spontaneous clearance of the HEV infection.





Autor: Diana Vassallo, Mir Mubariz Husain, Shaun Greer, Stephen McGrath, Samreen Ijaz, and Durga Kanigicherla

Fuente: https://www.hindawi.com/



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