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Case Reports in Oncological Medicine - Volume 2017 2017, Article ID 8654326, 9 pages - https:-doi.org-10.1155-2017-8654326

Case Report

Department of Pulmonary Medicine, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, Greece

Department of Medical Oncology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, Greece

Society for Study of the Clonal Heterogeneity of Neoplasia, Ioannina, Greece

Department of Radiology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, Greece

Department of Pathology, Medical School, University of Ioannina, Stavros Niarchos Avenue, 45110 Ioannina, Greece

Correspondence should be addressed to Stergios Boussios

Received 6 December 2016; Revised 12 February 2017; Accepted 14 February 2017; Published 2 March 2017

Academic Editor: Jose I. Mayordomo

Copyright © 2017 Christos Kyriakopoulos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Malignant melanoma involving the respiratory tract is nearly always metastatic in origin, and primary tumors are extremely rare. Published data on primary pulmonary malignant melanomas are limited. Up to now 40 relevant cases have been reported in the English literature. Herein, we report a case of a 56-year-old female patient who presented with intracranial metastases due to primary pulmonary melanoma. She underwent bronchoscopy and died 5 months after the initial diagnosis despite the administered biochemotherapy and subsequent immunotherapy. To establish the diagnosis of primary pulmonary malignant melanoma, any extrapulmonary origin was excluded by detailed examination and radiographic imaging. Moreover, an extensive review of the literature regarding this rare entity has been performed.





Autor: Christos Kyriakopoulos, George Zarkavelis, Artemis Andrianopoulou, Alexandra Papoudou-Bai, Dimitrios Stefanou, Stergios Bouss

Fuente: https://www.hindawi.com/



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