Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCTReportar como inadecuado




Evaluation of the Macular, Peripapillary Nerve Fiber Layer and Choroid Thickness Changes in Behçet’s Disease with Spectral-Domain OCT - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

Journal of Ophthalmology - Volume 2014 2014, Article ID 865394, 8 pages -

Clinical Study

Department of Ophthalmology, Kayseri Research and Teaching Hospital, Kocasinan, Kayseri, Turkey

Department of Physical Medicine and Rehabilitation, Kayseri Research and Teaching Hospital, Turkey

Department of Biostatistics, Medical School, University of Erciyes, Turkey

Received 21 February 2014; Revised 4 April 2014; Accepted 4 April 2014; Published 24 April 2014

Academic Editor: Edward Manche

Copyright © 2014 Mustafa Ataş et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To assess the macular, choroid, and peripapillary nerve fiber layer thickness RNFL in Behçet’s disease BD patients with and without ocular involvement by means of optical coherence tomography OCT and compare these findings with healthy controls. Design. Eighty patients with BD and 40 healthy controls who were followed up at the Uveitis and Retina Clinic of the Kayseri Research and Education Hospital in Turkey were enrolled in this prospective study. Subjects and Controls. The patients with BD were divided into two groups according to the presence of ocular involvement. Group 1 consisted of 40 eyes of 40 patients with ocular involvement and group 2 consisted of 40 eyes of 40 patients without ocular involvement. Methods. All of the patients and controls underwent macular, choroid, and peripapillary nerve fiber layer thickness analysis with Spectralis domain OCT Spectralis OCT Heidelberg Engineering, Dossenheim, Germany. Main Outcome Measures. The differences in macular, choroid, and peripapillary nerve fiber layer thicknesses between groups were analyzed statistically. Results. Macular thickness was thinner in patients with BD than in the control group; this result was statistically significant P = 0.05. There was no statistically significant difference in thickness between RNFL analysis of the patients with BD and control subjects. However, the BD patients with ocular involvement had statistically significant thinning in RNFL compared with BD patients without ocular involvement. Although the choroid was thicker in patients with BD than in the control group, it did not reach a statistically significant level P = 0.382. Conclusions. BD with ocular involvement may be associated with decreased macular and RNFL thickness measured with spectral-domain OCT.





Autor: Mustafa Ataş, İsa Yuvacı, Süleyman Demircan, Emel Güler, Orhan Altunel, Emine Pangal, Altan Göktaş, Serap Sütbeyaz,

Fuente: https://www.hindawi.com/



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