Heparin-Related Thrombocytopenia Triggered by Severe Status of Systemic Lupus Erythematosus and Bacterial InfectionReportar como inadecuado




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Case Reports in Rheumatology - Volume 2016 2016, Article ID 6571621, 5 pages -

Case Report

Department of Internal Medicine and Rheumatology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan

Department of Internal Medicine Research, Sasaki Institute, Sasaki Foundation, Tokyo 101-0062, Japan

Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo 113-8431, Japan

Department of Emergency and Critical Care Medicine, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan

Department of Internal Medicine and Nephrology, Juntendo University Nerima Hospital, Tokyo 177-8521, Japan

Received 21 May 2016; Accepted 17 August 2016

Academic Editor: Tsai-Ching Hsu

Copyright © 2016 Satoshi Suzuki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A patient with severe lupus nephritis developed thrombocytopenia during treatment with high-dose steroids. In addition to viral- or disease-induced cytopenia, the pathology was believed to arise from diverse contributing factors, such as thrombotic microangiopathy and heparin-related thrombocytopenia HIT. By combining plasma exchange therapy and intravenous cyclophosphamide, we successfully controlled the SLE activity and improved the thrombocytopenia. An antecedent bacterial infection or SLE activity is believed to have contributed to the concurrent HIT.





Autor: Satoshi Suzuki, Shihoko Nakajima, Taiki Ando, Keisuke Oda, Manabu Sugita, Kunimi Maeda, Yutaka Nakiri, and Yoshinari Takasa

Fuente: https://www.hindawi.com/



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