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SarcomaVolume 2008 2008, Article ID 654987, 5 pages

Clinical Study

King's College Hospital, Denmark Hill, London SE5 9RS, UK

Royal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UK

Oral and Maxillofacial Surgery, University Hospitals Birmingham, Birmingham B15 2TH, UK

Royal Orthopaedic Hospital, Bristol Road South, Birmingham B31 2AP, UK

Received 21 June 2007; Revised 26 November 2007; Accepted 12 February 2008

Academic Editor: Martin Robinson

Copyright © 2008 Rabindra P. Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We have retrospectively analysed the experience of a musculoskeletal oncological unit in the management of adult head and neck soft tissue sarcomas from 1990 to 2005.Thirty-six patients were seen, of whom 24 were treated at this unit, the remainder only receiving advice. The median age of the patients was 46 years. Most of the sarcomas were deep and of high or intermediate grade with a median size of 5.5 cm. Eleven different histological subtypes were identified. Wide excision was possible only in 21% of the cases. 42% of the patients developed local recurrence and 42% developed metastatic disease usually in the lungs. Overall survival was 49% at 5 years. Tumour size was the most important prognostic factor. Adult head and neck soft tissue sarcomas have a high mortality rate with a high risk of local recurrence and metastatic disease. The rarity of the disease would suggest that centralisation of care could lead to increased expertise and better outcomes.





Autor: Rabindra P. Singh, Robert J. Grimer, Nabina Bhujel, Simon R. Carter, Roger M. Tillman, and Adesegun Abudu

Fuente: https://www.hindawi.com/



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