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* Corresponding author 1 Division of General Medicine 2 Department of Orthopedic Surgery 3 Department of Biostatistics 4 Epidémiologie et Biostatistique Bordeaux 5 CePReF - Centre de Prise en charge, de Recherche et de Formation 6 Yale University New Haven 7 Department of Infectious Disease Boston 8 Center for AIDS Research Cambridge 9 Division of Infectious Disease 10 Department of Medicine 11 Department of Health Policy and Management 12 Department of Genetics Boston

Abstract : BACKGROUND: Data from HIV treatment programs in resource-limited settings show extensive rates of loss to follow-up LTFU ranging from 5% to 40% within 6 mo of antiretroviral therapy ART initiation. Our objective was to project the clinical impact and cost-effectiveness of interventions to prevent LTFU from HIV care in West Africa. METHODS AND FINDINGS: We used the Cost-Effectiveness of Preventing AIDS Complications CEPAC International model to project the clinical benefits and cost-effectiveness of LTFU-prevention programs from a payer perspective. These programs include components such as eliminating ART co-payments, eliminating charges to patients for opportunistic infection-related drugs, improving personnel training, and providing meals and reimbursing for transportation for participants. The efficacies and costs of these interventions were extensively varied in sensitivity analyses. We used World Health Organization criteria of



Autor: Elena Losina - Hapsatou Touré - Lauren Uhler - Xavier Anglaret - A David Paltiel - Eric Balestre - Rochelle Walensky - Eugène M

Fuente: https://hal.archives-ouvertes.fr/



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