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Spectroscopy - Volume 24 2010, Issue 1-2, Pages 99-104



Department of Medical Physics, Medical School, University of Ioannina, Ioannina, Greece

Department of Medical Physics, Medical School, University of Ioannina, Ioannina 45110, Greece



Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Fourier transform infrared spectroscopy combined with multivariate analysis was performed on a series of bone samples in order to investigate possible differences in the molecular fingerprint based on classification either between different sex and bone sites. Cortical femoral, tibia and ulna samples from five male and five female normal Wistar rats were analysed. PCA analysis classified successfully sex-related spectra since the first three principal components explained 95% of the total variance. This was not the case for bone site-related spectra. In all cases, an important aspect is the ionic exchange of phosphate and carbonate ions.





Autor: Nikolaos Kourkoumelis and Margaret Tzaphlidou

Fuente: https://www.hindawi.com/



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