Cerebellar-dependent delay eyeblink conditioning in adolescents with Specific Language ImpairmentReportar como inadecuado




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Journal of Neurodevelopmental Disorders

, Volume 2, Issue 4, pp 243–251

First Online: 10 August 2010Received: 02 August 2009Accepted: 28 July 2010

Abstract

Cerebellar impairments have been hypothesized as part of the pathogenesis of Specific Language Impairment SLI, although direct evidence of cerebellar involvement is sparse. Eyeblink Conditioning EBC is a learning task with well documented cerebellar pathways. This is the first study of EBC in affected adolescents and controls. 16 adolescent controls, 15 adolescents with SLI, and 12 adult controls participated in a delay EBC task. Affected children had low general language performance, grammatical deficits but no speech impairments. The affected group did not differ from the control adolescent or control adult group, showing intact cerebellar functioning on the EBC task. This study did not support cerebellar impairment at the level of basic learning pathways as part of the pathogenesis of SLI. Outcomes do not rule out cerebellar influences on speech impairment, or possible other forms of cerebellar functioning as contributing to SLI.

KeywordsSpecific Language Impairment Cerebellum Eyeblink conditioning Conditioned learning Adolescence  Download fulltext PDF



Autor: Adam B. Steinmetz - Mabel L. Rice

Fuente: https://link.springer.com/







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