Characterization of a non linear fractional model of electrode-tissue impedance for neuronal stimulationReportar como inadecuado

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1 IPB, ENSEIRB-MATMECA, IMS - Institut Polytechnique de Bordeaux, ENSEIRB-MATMECA, laboratoire IMS 2 IMN - Institut des Maladies Neurodégénératives Bordeaux

Abstract : The design of neuro-stimulators must include a realistic model of electrode-tissue interface. Complex electrochemical phenomena associated to high levels of stimulation current give fractional and non linear behavior to this interface that simple linearized models fail to fit. This paper describes both a measurement protocol based on biphasic current-controlled solicitations and a modeling procedure relying on an original approach of multi-model, taking into account the non-linear and fractional effects. This model fits correctly the measurement results with current levels varying from 50μA to 1mA. Furthermore the whole characterization protocol can be safely transposed to in vivo measurements.

Keywords : bioelectric potentials biological tissues biomedical electrodes electric immittance measurement electrochemical electrodes neurophysiology physiological models biphasic current-controlled solicitations electrochemical phenomena electrode-tissue impedance electrode-tissue interface model neuronal stimulation nonlinear fractional model stimulation current Artificial neural networks Biomedical measurement Computational modeling Electric variables measurement Electrodes Fractals Generators

Autor: Florian Kolbl - Jocelyn Sabatier - Gilles N-Kaoua - Frédéric Naudet - Emilie Faggiani - Abdelhamid Benazzouz - Sylvie Renaud -



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