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BioMed Research International - Volume 2016 2016, Article ID 7240864, 5 pages -

Research Article

Department of Pediatric Intensive Care Unit, Dicle University Medical School, 21010 Diyarbakir, Turkey

Dicle University School of Medicine, Clinical Microbiology and Infectious Diseases, 21010 Diyarbakir, Turkey

Department of Pediatrics, Dicle University Medical School, 21010 Diyarbakir, Turkey

Department of Pediatric Infectious Diseases, Diyarbakir Children’s Hospital, Diyarbakir, Turkey

Received 22 October 2015; Revised 8 January 2016; Accepted 18 January 2016

Academic Editor: Benoît Stijlemans

Copyright © 2016 Fesih Aktar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The objective of this study was to determine the rate, independent risk factors, and outcomes of healthcare-associated infections in pediatric patients. This study was performed between 2011 and 2014 in pediatric clinic and intensive care unit. 86 patients and 86 control subjects were included in the study. Of 86 patients with nosocomial infections NIs, there were 100 NIs episodes and 90 culture growths. The median age was 32.0 months. The median duration of hospital stay of the patients was 30.0 days. The most frequent pathogens were Coagulase-negative Staphylococcus, Acinetobacter spp., Klebsiella spp., and Candida spp. Unconsciousness, prolonged hospitalization, transfusion, mechanical ventilation, use of central venous catheter, enteral feeding via a nasogastric tube, urinary catheter, and receiving carbapenems and glycopeptides were found to be significantly higher in NIs patients. Multivariate logistic regression analysis showed prolonged hospitalization, neutropenia, and use of central venous catheter and carbapenems as the independent risk factors for NIs. In the univariate analysis, unconsciousness, mechanical ventilation, enteral feeding, use of enteral feeding via a nasogastric tube, H2 receptor blockers, and port and urinary catheter were significantly associated with mortality. In the multiple logistic regression analysis, only mechanical ventilation was found as an independent predictor of mortality in patients with NIs.





Autor: Fesih Aktar, Recep Tekin, Ali Güneş, Cevat Ülgen, İlhan Tan, Sabahattin Ertuğrul, Muhammet Köşker, Hasan Balık, Du

Fuente: https://www.hindawi.com/



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