Reorganization of early visual cortex functional connectivity following selective peripheral and central visual lossReportar como inadecuado




Reorganization of early visual cortex functional connectivity following selective peripheral and central visual loss - Descarga este documento en PDF. Documentación en PDF para descargar gratis. Disponible también para leer online.

1 Institut de la Vision 2 CIC Quinze-Vingts 3 Hôpital Foch Suresnes 4 UCL - University College of London London 5 Fondation Ophtalmologique Adolphe de Rotschild 6 University of Pittsburgh Pittsburg 7 HUJ - The Hebrew University of Jerusalem 8 Geneva University Hospitals

Abstract : Behavioral alterations emerging after central or peripheral vision loss suggest that cerebral reorganization occurs for both the afferented and deafferented early visual cortex EVC. We explored the functional reorganization of the central and peripheral EVC following visual field defects specifically affecting central or peripheral vision. Compared to normally sighted, afferented central and peripheral EVC enhance their functional connectivity with areas involved in visual processing, whereas deafferented central and peripheral EVC increase their functional connectivity with more remote regions. The connectivity pattern of afferented EVC suggests adaptive changes that might enhance the visual processing capacity whereas the connectivity pattern of deafferented EVC may reflect the involvement of these regions in high-order mechanisms. Characterizing and understanding the plastic changes induced by these visual defects is essential for any attempt to develop efficient rehabilitation strategies.





Autor: Norman Sabbah - Nicolae Sanda - Colas N. Authié - Saddek Mohand-Saïd - José-Alain Sahel - Christophe Habas - Amir Amedi - Avin

Fuente: https://hal.archives-ouvertes.fr/



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