Is Bisphosphonate-Related Osteonecrosis of the Jaw an Infection A Histological and Microbiological Ten-Year SummaryReportar como inadecuado




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International Journal of DentistryVolume 2014 2014, Article ID 452737, 7 pages

Review Article

University of Arkansas for Medical Sciences UAMS, College of Medicine, Little Rock, AR 72205, USA

Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA

Department of Biostatistics, UAMS, Little Rock, AR 72205, USA

Department of Otolaryngology-Head and Neck Surgery, UAMS, 4301 W. Markham Street No. 543, Little Rock, AR 72205, USA

Received 10 March 2014; Accepted 26 May 2014; Published 24 June 2014

Academic Editor: Giuliano Ascani

Copyright © 2014 A. M. Hinson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The role of infection in the etiology of bisphosphonate-related osteonecrosis of the jaw BRONJ is poorly understood. Large-scale epidemiological descriptions of the histology and microbiology of BRONJ are not found in the literature. Herein, we present a systematic review of BRONJ histology and microbiology including demographics, immunocompromised associations, clinical signs and symptoms, disease severity, antibiotic and surgical treatments, and recovery status validating that infection should still be considered a prime component in the multifactorial disease.





Autor: A. M. Hinson, C. W. Smith, E. R. Siegel, and B. C. Stack Jr.

Fuente: https://www.hindawi.com/



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